Pathway results from the chicken data set using GOTM, Pathway studio and ingenuity softwares

Abstract : Background: As presented in the introduction paper, three sets of differentially regulated genes were found after the analysis of the chicken infection data set from EADGENE. Different methods were used to interpret these results. Results: GOTM, Pathway Studio and Ingenuity softwares were used to investigate the three lists of genes. The three softwares allowed the analysis of the data and highlighted different networks. However, only one set of genes, showing a differential expression between primary and secondary response gave significant biological interpretation. Conclusion: Combining these databases that were developed independently on different annotation sources supplies a useful tool for a global biological interpretation of microarray data, even if they may contain some imperfections (e.g. gene not or not well annotated).
Document type :
Journal articles
Complete list of metadatas

Cited literature [4 references]  Display  Hide  Download

https://hal-agrocampus-ouest.archives-ouvertes.fr/hal-00730039
Contributor : Céline Martel <>
Submitted on : Tuesday, March 5, 2013 - 4:38:08 PM
Last modification on : Saturday, April 13, 2019 - 1:12:15 AM
Long-term archiving on : Friday, March 31, 2017 - 12:38:27 PM

File

1753-6561-3-S4-S11.pdf
Publisher files allowed on an open archive

Identifiers

Citation

Agnès Bonnet, Sandrine Lagarrigue, Laurence Liaubet, Christèle Robert Robert-Granié, Magali San Cristobal, et al.. Pathway results from the chicken data set using GOTM, Pathway studio and ingenuity softwares. BMC Proceedings, BioMed Central, 2009, 3 (Suppl 4), pp.1-6. ⟨10.1186/1753-6561-3-S4-S11⟩. ⟨hal-00730039⟩

Share

Metrics

Record views

197

Files downloads

246